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Iduronate Sulfatase

Spanish: Factor Correctivo de Hunter

Description

Iduronate Sulfatase is an enzyme that plays a crucial role in the metabolism of glycosaminoglycans, specifically in the breakdown of dermatan sulfate and heparan sulfate. Deficiency of this enzyme leads to Hunter syndrome, a genetic disorder characterized by various physical and cognitive impairments.

Interpreter Notes

Interpreters should be aware that the term 'Factor Correctivo de Hunter' may be used interchangeably with 'Iduronate Sulfatase' in clinical settings. It is important to maintain a formal register and avoid colloquial terms. Be cautious of regional variations in terminology and ensure clarity in communication.

Example Sentences

EN: The patient was diagnosed with a deficiency of Iduronate Sulfatase, leading to Hunter syndrome.

ES: El paciente fue diagnosticado con una deficiencia del Factor Correctivo de Hunter, que conduce al síndrome de Hunter.

Common Interpreter Mistakes

Confusing 'Iduronate Sulfatase' with similar enzyme names; mispronouncing 'Factor Correctivo de Hunter' as 'Factor Corrector de Hunter'; mixing up Hunter syndrome with other lysosomal storage disorders.

Pronunciation (EN):

Pronunciation (ES):

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Term Last Updated: January 5, 2026